Tianjiao Chu

The paper identifies putative vaginal epithelial stem cells (veSCs) in the premenopausal human vagina using single-cell RNA sequencing and functional assays.

This study identifies PHF13 as a chromatin regulator critical for trophoblast stemness and differentiation, showing its role in maintaining stemness and restricting differentiation through gene regulatory networks.

The paper validates three TEX11 variants associated with human azoospermia by generating mouse models and observing fertility and spermatogenesis defects.

This study shows that single-spun plasma is sufficient for accurate cfDNA analysis, challenging the need for double centrifugation in liquid biopsy workflows.

The paper investigates the role of C19MC microRNAs in trophoblasts, showing they suppress innate immune activation by interfering with TLR3.

The paper uses a multiomics approach to identify placental network differences among obstetric syndromes, finding unique signatures associated with specific clinical outcomes.