Depletion of border-associated macrophages impairs CSF flow and exacerbates extranuclear mutant Huntingtin aggregation in the zQ175DN mouse model of Huntington disease
Yanli Jiang, Rahul Sondawle, Helen Moniz, Emily Mu, Wenzhen Duan
This study shows that depletion of border-associated macrophages in HD mice impairs CSF flow and increases extranuclear mutant huntingtin aggregation.
bioRxiv · Sep 30, 2026 · PreprintNeuroscience