Jiadi Xu

This study shows that restoring aquaporin-4 in a Huntington disease mouse model improves glymphatic function and reduces disease-related molecular and motor phenotypes.

This study identifies a mechanism by which reactive astrocytes drive neurodegeneration in synucleinopathies through extracellular acidification and neuronal ASIC1a activation.

This paper develops a multimodal imaging platform to track human cortical organoids in mice after stroke, showing their survival and maturation in specific brain regions.

The paper identifies cell type-specific transcriptomic changes in 5XFAD mice that link BBB dysfunction and metabolic dysregulation to early AD pathogenesis.

This study evaluates ultrafast Z-spectroscopy MRI with pH correction for measuring mitochondrial oxidative phosphorylation in human skeletal muscle.

This study uses MRI and fluorescence imaging to show impaired glymphatic function in a mouse model of Huntington disease, suggesting it as a potential biomarker and therapeutic target.

This study shows that HTT silencing in premanifest HD mice delays disease onset and slows progression, using CBVa as a noninvasive biomarker.

This study uses MEMRI to visualize laminar-specific spinal cord pathways in rats, showing T1 signal enhancement in specific laminae after MnCl2 administration.