Effects Of Curcumin Nanoformulations On Cellular Function In Niemann-Pick Disease Type C Astrocytes
Emily Maguire, Luke J. Haslett, Joanne L. Welton, Helen Waller-Evans, Jule Goike, Emily H. Clark, Harry R. Knifton, Ravin Shrestha, Kim Wager, Richard Webb, Emyr Lloyd-Evans
This study evaluates commercial curcumin nanoformulations in NPC1-deficient astrocytes, finding that only two reduce lysosomal lipid storage while others increase storage or reduce viability.
bioRxiv · May 9, 2017 · PreprintPharmacology & Toxicology