A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy
Georgios A. Kaissis, Sebastian Ziegelmayer, Fabian Karl Lohöfer, Katja Steiger, Hana Algül, Alexander Muckenhuber, Hsi-Yu Yen, Ernst J. Rummeny, Helmut Frieß, Roland Michael Schmid, Wilko Weichert, Jens Thomas Siveke, Rickmer Braren
This paper develops a machine learning model to predict molecular subtypes of PDAC from radiomic features, showing differential chemotherapy response based on subtype.
PLoS ONE · Oct 2, 2019Peer-reviewedBioinformatics