Author

Henk Granzier

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alfredo H Bongiorno· 1 shared Arian MansuriD· 1 shared Carina Wallgren‐PetterssoniD· 1 shared Edmar ZanoteliiD· 1 shared Esmat Karimi· 1 shared Grace Tate· 1 shared Hyewon Han· 1 shared Janet ShiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetics

Alfredo H Bongiorno

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2 papers

Recent·Most cited

KLHL41 orchestrates sarcomere assembly and size to drive skeletal muscle hypertrophy in vivo

Hyewon Han, Janet Shi, Alfredo H Bongiorno, Arian Mansur, Jeffrey J. Widrick, Grace Tate, Sehajpreet Gill, Esmat Karimi, Henk Granzier, Jeffrey R. Moore, Vandana Gupta

This study identifies KLHL41's role in sarcomere assembly and muscle growth in zebrafish models of nemaline myopathy, revealing its importance in myofibril formation and cross-bridge regulation.

bioRxiv · May 30, 2025 · PreprintGenetics

Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle

Jenni M. Laitila, Robert A. E. Seaborne, Natasha Ranu, Justin S. Kolb, Carina Wallgren‐Pettersson, Nanna Witting, John Vissing, Juan Jesus Vilchez, Edmar Zanoteli, Johanna Palmio, Sanna Huovinen, Henk Granzier, Julien Ochala

This study tests Mavacamten's ability to rescue metabolic dysregulation in nebulin-deficient muscle, finding it effective in vitro but ineffective in vivo for reversing the proteome changes.

The Journal of Physiology · Aug 31, 2024Peer-reviewedPhysiology