Author

Jenni M. Laitila

University of CopenhagenORCID 0000-0002-0076-3038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Julien OchalaiD· 3 shared Robert A. E. SeaborneiD· 3 shared Atul S. DeshmukhiD· 2 shared Christopher T. A. LewisiD· 2 shared Edmar ZanoteliiD· 2 shared Lola Savoure· 2 shared Roger Moreno‐JusticiaiD· 2 shared Agata BakiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersPhysiology

Julien OchalaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy

Robert A. E. Seaborne, Roger Moreno‐Justicia, Jenni M. Laitila, Christopher T. A. Lewis, Lola Savoure, Edmar Zanoteli, Michael William Lawlor, Heinz Jungbluth, Atul S. Deshmukh, Julien Ochala

This paper introduces SMPFO, a method combining fluorescence assays and proteome profiling to study skeletal muscle, revealing reduced myofiber subtype divergence in nemaline myopathy.

The Journal of Physiology · May 1, 2025Peer-reviewedPhysiology

Dysregulated Skeletal Muscle Myosin Super-relaxation and Energetics in Type II Diabetes

Christopher T. A. Lewis, Roger Moreno‐Justicia, Lola Savoure, Enrique Calvo, Agata Bak, Jenni M. Laitila, Robert A. E. Seaborne, Steen Larsen, Hiroyuki Iwamoto, Marina Cefis, José A. Morais, Gilles Gouspillou, Jorge Alegre‐Cebollada, Thomas James Hawke, Jesús Vázquez, , Julien Ochala

This study investigates altered myosin super-relaxation and energy metabolism in type II diabetes using muscle biopsies and proteomic analyses, finding increased super-relaxation and reduced ATP demand.

Diabetologia · Apr 28, 2025Peer-reviewedCell Biology

Myosin ATPase inhibition fails to rescue the metabolically dysregulated proteome of nebulin-deficient muscle

Jenni M. Laitila, Robert A. E. Seaborne, Natasha Ranu, Justin S. Kolb, Carina Wallgren‐Pettersson, Nanna Witting, John Vissing, Juan Jesus Vilchez, Edmar Zanoteli, Johanna Palmio, Sanna Huovinen, Henk Granzier, Julien Ochala

This study tests Mavacamten's ability to rescue metabolic dysregulation in nebulin-deficient muscle, finding it effective in vitro but ineffective in vivo for reversing the proteome changes.

The Journal of Physiology · Aug 31, 2024Peer-reviewedPhysiology