Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis
John A. Lees, Bart Ferwerda, Philip H. C. Kremer, Nicole E. Wheeler, Mercedes Valls Serón, Nicholas J. Croucher, Rebecca A. Gladstone, Hester J. Bootsma, Nynke Y. Rots, Alienke J. Wijmenga‐Monsuur, Elisabeth A. M. Sanders, Krzysztof Trzciński, Anne L. Wyllie, Aeilko Having Zwinderman, Leonard H. van den Berg, , Diederik van de Beek
The paper uses genome-wide association studies to show human and pneumococcal genetic variation influences susceptibility and severity of pneumococcal meningitis.
Nature Communications · May 15, 2019Peer-reviewedGenomics