Anne L. Wyllie

This study shows that pneumococcal growth kinetics are influenced by capsular serotype, lineage, and genetic background rather than specific loci.

This paper introduces SeroBA(v2.0), a tool for pneumococcal serotyping, and SeroBAnk, a resource for capsular diversity, which accurately identifies 102 serotypes and supports community contributions for updates.

This study evaluates the storage stability of non-encapsulated pneumococci in saliva, finding that NCC2 strains are less stable than NCC1, and that extraction-free methods may better detect NCC2 strains.

The paper develops a novel multiplex qPCR assay to detect and classify non-encapsulated pneumococci (NESp) by targeting aliC and aliD genes, showing high specificity and prevalence in saliva samples.

This paper develops tiled amplicon sequencing panels for whole-genome sequencing of pathogenic bacteria without culturing, enabling drug resistance classification from clinical samples.

The paper uses genome-wide association studies to show human and pneumococcal genetic variation influences susceptibility and severity of pneumococcal meningitis.