Author

Hezlin Marzook

University of Sharjah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Firdos AhmadiD· 3 shared Rizwan QaisariD· 3 shared Anamika GuptaiD· 2 shared Dhanendra TomariD· 1 shared James Robert WoodgettiD· 1 shared Manju Nidagodu JayakumariD· 1 shared Mohamed A Saleh· 1 shared Mohamed A. SalehiD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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3 shared papersCell Biology

Firdos AhmadORCID

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Author profile →

3 papers

Recent·Most cited

GSK-3alpha-BNIP3 axis promotes mitophagy in human cardiomyocytes under hypoxia

Hezlin Marzook, Anamika Gupta, Manju Nidagodu Jayakumar, Mohamed A. Saleh, Dhanendra Tomar, Rizwan Qaisar, Firdos Ahmad

This study identifies a novel mechanism by which GSK-3 promotes mitophagy in human cardiomyocytes under hypoxia through BNIP3 upregulation and interaction.

Free Radical Biology and Medicine · May 28, 2024Peer-reviewedCell Biology

Natural compound screening predicts novel GSK-3 isoform-specific inhibitors

Firdos Ahmad, Anamika Gupta, Hezlin Marzook, James Robert Woodgett, Mohamed A Saleh, Rizwan Qaisar

This study identifies two natural compounds, Psoralidin and Rosmarinic acid, as GSK-3 isoform-specific inhibitors with differential potency against GSK-3 and GSK-3β.

Biochimie · May 7, 2024Peer-reviewedBiochemistry

Nicotinamide riboside kinase-2 inhibits JNK pathway and limits dilated cardiomyopathy in mice with chronic pressure overload

Syeda Kiran Shahzadi, Hezlin Marzook, Rizwan Qaisar, Firdos Ahmad

This study shows that NRK-2 protects against pressure overload-induced cardiac remodeling by inhibiting JNK pathway activation and mitochondrial dysfunction in mice.

Clinical Science · Jan 1, 2022Peer-reviewedMolecular Biology