Allele-Resolved Hybrid Embryos Reveal the Fates of Regulatory Divergence
Jiali Lei, Laurence A. Lemaire, Hidehiko Hashimoto, Liam Rodman, Michael Levine, Cao Chen
The paper tracks regulatory divergence in hybrid embryos of Ciona species, showing how allelic differences are maintained or remodeled in lineage-specific ways and how GRN hierarchy influences allelic divergence.
bioRxiv · Sep 15, 2026 · PreprintDevelopmental Biology