Laurence A. Lemaire

The paper tracks regulatory divergence in hybrid embryos of Ciona species, showing how allelic differences are maintained or remodeled in lineage-specific ways and how GRN hierarchy influences allelic divergence.

This paper investigates the role of Lmx1 in Ciona neural tube closure, finding that its knockdown causes defects and overexpression disrupts cell intercalation, suggesting a conserved role in chordate morphogenesis.

The paper identifies a transcriptional network involving Lmx1, Cdkn1b, and Msx that coordinates neural tube closure in Ciona, showing a pair-rule-like pattern and cell-cycle regulation.

The paper investigates cereblon's role in muscle differentiation in Ciona embryos, finding it regulates contractility gene expression timing through interactions with Tbx6 and Snail.