Serotonin in the orbitofrontal cortex enhances cognitive flexibility
Jung Ho Hyun, Patrick Hannan, Hideki Iwamoto, Randy Blakely, Hyung‐Bae Kwon
This study shows that serotonin release from the dorsal raphe nuclei to the orbitofrontal cortex enhances reversal learning by increasing neuronal excitability and synaptic plasticity.
bioRxiv · Mar 9, 2023 · PreprintNeuroscience