Tracking global changes induced in the CD4 T cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.
Niclas Thomas, Katharine Best, Mattia Cinelli, Shlomit Reich-Zeliger, Hila Gal, Eric Shifrut, Asaf Madi, Nir Friedman, John Shawe-Taylor, Benny Chain
This study tracks changes in CD4 T cell receptor repertoires after immunization using short CDR3 sequences, showing distinct repertoires at different time points post-vaccination.
bioRxiv · Jan 17, 2014Immunology