Sequence and primer independent stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding
Katharine Best, Theres Oakes, James M Heather, John Shawe-Taylor, Benny Chain
This study uses single molecule barcoding with HTS to reveal stochastic heterogeneity in PCR amplification efficiency, independent of sequence or experimental conditions.
bioRxiv · Nov 13, 2014Molecular Biology