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Hila S. Swindell

University of California System

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Molecular Biology· 1

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Approach:experimental assay· 1

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Aijun WangiD· 1 shared Gary Scott LeiserowitziD· 1 shared Hanna J. KosteriD· 1 shared Rachel R. MizenkoiD· 1 shared Randy P. CarneyiD· 1 shared Tatu RojaliniD· 1 shared Terza BrostoffiD· 1 shared

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Aijun WangORCID

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Molecular BiologyJournal of NanobiotechnologyPeer-reviewedAug 21, 2021

Tetraspanin immunocapture phenotypes extracellular vesicles according to biofluid source but may limit identification of multiplexed cancer biomarkers

Rachel R. Mizenko, Terza Brostoff, Tatu Rojalin…·Randy P. Carney

The paper analyzes single extracellular vesicles to show that tetraspanin profiles vary by source but not isolation method, and that capture methods can bias apparent protein expression and diagnostic sensitivity.

162 citationstop 1%

experimental assay

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