The tumor suppressor FBW7 and the vitamin D receptor are mutual cofactors.
Reyhaneh Salehi-Tabar, Babak Memari, Hilary Wong, Vassil Dimitrov, Natacha Rochel, John H. White
This study shows that the vitamin D receptor (VDR) and FBW7 are mutual cofactors that enhance each other's function, promoting cancer prevention through accelerated degradation of target proteins.
Molecular Cancer Research · Jan 3, 2019Peer-reviewedMolecular Biology