Genetic analysis of the X-linked Adrenoleukodystrophy ABCD1 gene in Drosophila uncovers a role in Peroxisomal dynamics
Joshua Manor, Sharayu V. Jangam, Hyung-Lok Chung, Pranjali Bhagwat, Jonathan Andrews, Hillary Chester, Shu Kondo, Saurabh Srivastav, Juan Botas, Ann B. Moser, Suzette M Huguenin, Michael F. Wangler
This paper investigates the role of the Drosophila ABCD1 ortholog in peroxisomal dynamics and shows that human ABCD1 overexpression inhibits peroxisomal biogenesis.
bioRxiv · Sep 23, 2024 · PreprintGenetics