Dimeric Cin8 motors have an inherent plus-end bias and weak inter-head coordination
Himanshu Pandey, Tzu-Chen Ma, Eric Bonventre, Luke M. Rice, Larisa Gheber, William Olaf Hancock
This study investigates the bidirectional motility of Cin8 kinesin-5 dimers, finding a plus-end bias and weak inter-head coordination, suggesting directional switching is regulated by coordination levels.
Biophysical Journal · Mar 7, 2026Peer-reviewedBiophysics