Author

Himari Imaya Gunasinghe

Weill Cornell Medicine

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Cancer Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

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Elizabeth Granowsky· 1 shared Jinru ShiaiD· 1 shared Kevan ChuiD· 1 shared Lukas E. DowiD· 1 shared Marie J. ParsonsiD· 1 shared Rona D. YaegeriD· 1 shared Salvador AlonsoiD· 1 shared

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2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Elizabeth Granowsky

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1 paper

Recent·Most cited

Concurrent genetic and non-genetic resistance mechanisms to KRAS inhibition in CRC

Salvador Alonso, Kevan Chu, Marie J. Parsons, Elizabeth Granowsky, Himari Imaya Gunasinghe, Jinru Shia, Rona D. Yaeger, Lukas E. Dow

This study identifies genetic and non-genetic resistance mechanisms to KRAS inhibition in CRC using single-cell spatial transcriptomics and exome sequencing, revealing inflammatory and fetal-like transcriptional signatures associated with resistance.

bioRxiv · Aug 5, 2025 · PreprintCancer Biology