Author

Hirokazu Enomoto

Keio University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Organism:zebrafish· 1

Frequent Co-Authors

Akinori KimuraiD· 1 shared Alexander Gasch· 1 shared Atsushi KawakamiiD· 1 shared Fumiyuki HattoriiD· 1 shared Keiichi FukudaiD· 1 shared Mayumi OdaiD· 1 shared Nishant MittaliD· 1 shared Ruri KanedaiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Akinori KimuraORCID

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1 paper

Recent·Most cited

Perturbation of the titin/MURF1 signaling complex is associated with hypertrophic cardiomyopathy in a fish model and in human patients.

Yuta Higashikuse, Nishant Mittal, Takuro Arimura, Sung Han Yoon, Mayumi Oda, Hirokazu Enomoto, Ruri Kaneda, Fumiyuki Hattori, Takeshi Suzuki, Atsushi Kawakami, Alexander Gasch, Tetsushi Furukawa, Siegfried Labeit, Keiichi Fukuda, Akinori Kimura, Shinji Makino

The paper identifies mutations in the titin Ig domain associated with hypertrophic cardiomyopathy in both a fish model and human patients, showing increased titin-MURF1 binding and degradation.

Disease Models & Mechanisms · Jan 1, 2019Peer-reviewedDevelopmental Biology