Author
Heidelberg UniversityORCID 0000-0002-9009-210XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Robbert J. van der Pijl, Jochen Gohlke, Joshua G. Strom…·Coen A. C. Ottenheijm
The paper identifies MARPs as key modulators of titin-based mechanotransduction and shows mTORC1 regulates longitudinal muscle hypertrophy in response to stretch.
Fernando Silva Ribeiro, Luis D Chinait, Maria Rita C Rodrigues…·Anselmo Sigari Moriscot
This study shows that MyoMed-205 improves exercise capacity in rats without altering soleus muscle structure.
Fernando Silva Ribeiro, Paulo R. Jannig, Siegfried Labeit, Anselmo Sigari Moriscot
This study shows that MyoMed-205, a small-molecule targeting MuRF1, prevents diaphragm atrophy and dysfunction after 12 hours of unilateral denervation in rats by enhancing muscle structure, function, and reducing fibrosis.
Yuta Higashikuse, Nishant Mittal, Takuro Arimura…·Shinji Makino
The paper identifies mutations in the titin Ig domain associated with hypertrophic cardiomyopathy in both a fish model and human patients, showing increased titin-MURF1 binding and degradation.