Engineering a model cell for rational tuning of GPCR signaling
W. M. Shaw, Hitoshi Yamauchi, Jack Mead, Glen-Oliver F. Gowers, David J. Bell, David Öling, Niklas Larsson, Mark J Wigglesworth, Graham Ladds, Tom Ellis
The paper constructs a synthetic GPCR signaling system in yeast to predictably tune cellular responses to stimuli using computational and experimental methods.
Cell · Apr 1, 2019Peer-reviewedSynthetic Biology