Protection against reinfection with Mycobacterium tuberculosis extends across heterologous Mtb lineages
Andrew W. Simonson, Michael C. Chao, Luke E Hood, Rachel Donlan, Forrest F. Hopkins, Michael R. Chase, Andrew Julian Vickers, Alanna Callendrello, Edwin C. Klein, HJacob Borish, Marshall Malin, Pauline A Maiello, Charles A. Scanga, Philana Ling Lin, Sarah M. Fortune, JoAnne L. Flynn
The study shows that prior Mtb infection protects against reinfection with a genetically distinct strain in macaques, suggesting broad vaccine efficacy across Mtb lineages.
Mucosal Immunology · Nov 3, 2025Peer-reviewedImmunology