The proSAAS chaperone provides neuroprotection and attenuates transsynaptic α-synuclein spread in rodent models of Parkinson's disease
Iris Lindberg, Zhan Shu, Hoa A. Lam, Michael Helwig, Nur Yucer, Alex Laperle, Clive Niels Svendsen, Donato A. Di Monte, Nigel T. Maidment
This paper demonstrates that proSAAS overexpression protects dopaminergic neurons and reduces transsynaptic α-synuclein spread in Parkinson's disease models.
Journal of Parkinson s Disease · May 6, 2022Peer-reviewedNeuroscience