A combination of major histocompatibility complex (MHC) I overexpression and type I interferon induce mitochondrial dysfunction in human skeletal myoblasts.
Anastasia Thoma, Razan Alomosh, Holly L. Bond, Tania Akter‐Miah, Nasser Al‐Shanti, Hans Degens, Vanja Pekovic‐Vaughan, Adam P. Lightfoot
This study shows that MHC-I overexpression and type I IFNs together worsen mitochondrial dysfunction in human skeletal myoblasts.
Journal of Cellular Physiology · Oct 9, 2024Peer-reviewedCell Biology