Divergent effects of C4a, C4adesArg, and thrombin on platelet aggregation and phosphorylation of ERK and Akt in human endothelial cells.
Mengyao Liu, Vy K. Tran Luu, Hongbin Wang
This study compares the effects of C4a, C4adesArg, and thrombin on ERK and Akt phosphorylation and platelet aggregation in human endothelial cells, revealing differences in receptor activation and signaling outcomes.
bioRxiv · Mar 13, 2024 · PreprintImmunology