Author

Hongbin Wang

Northwestern UniversityORCID 0000-0003-4957-0509Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jane FrederickiD· 1 shared Sheng Hui· 1 shared Vadim BackmaniD· 1 shared Xin WangiD· 1 shared Zhe JiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Jane FrederickORCID

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1 paper

Recent·Most cited

GenomicsNAR Genomics and BioinformaticsPeer-reviewedApr 9, 2021

Spike-in normalization for single-cell RNA-seq reveals dynamic global transcriptional activity mediating anti-cancer drug response

Xin Wang, Jane Frederick, Hongbin Wang…·Zhe Ji

This study uses spike-in normalization in single-cell RNA-seq to reveal dynamic transcriptional changes in cancer cells responding to anti-cancer drugs, identifying gene states and regulatory modules linked to drug efficacy.

8 citations

humanscRNA-seq

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