Spatial joint profiling of DNA methylome and transcriptome in mammalian tissues
Chin Nien Lee, Hongxiang Fu, Angelysia Cardilla, Wanding Zhou, Yanxiang Deng
This paper introduces a method for spatial co-profiling of DNA methylation and transcriptome in mammalian tissues, revealing spatial patterns and their interplay in development and brain function.
bioRxiv · Jul 1, 2025 · PreprintGenomics