Author
Chin Nien Lee
University of PennsylvaniaORCID 0000-0002-5867-5962Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2025-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 37 mutual co-author links4 papers
Recent·Most cited
- BioengineeringbioRxivPreprint
Live Spatial Transcriptomics Enables Longitudinal Tissue Mapping
David E. Reynolds, Sangmo Lee, Chin Nien Lee…·Jina Ko
This paper introduces Live-ST, a method for longitudinal spatial transcriptomics, and demonstrates its use in tracking drug response in melanoma tissues.
DOI 10.64898/2026.10.28.761959 - GenomicsbioRxivPreprint
Spatial joint profiling of DNA methylome and transcriptome in mammalian tissues
Chin Nien Lee, Hongxiang Fu, Angelysia Cardilla…·Yanxiang Deng
This paper introduces a method for spatial co-profiling of DNA methylation and transcriptome in mammalian tissues, revealing spatial patterns and their interplay in development and brain function.
DOI 10.1101/2025.07.01.662607 - GeneticsNature MethodsPeer-reviewed
Multiplexed spatial mapping of chromatin features, transcriptome, and proteins in tissues
Pengfei Guo, Liran Mao, Yu‐Fan Chen…·Yanxiang Deng
The paper introduces spatial-Mux-seq, a multi-modal spatial technology that profiles five modalities in tissues, revealing new insights into cell types, gene regulation, and epigenetic gradients in mouse embryos and brains.