Author

Hongzhi He

University of Florida Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew C. LiuiD· 2 shared Yang SheniD· 2 shared Carlos Enrique PradaiD· 1 shared Carolyn R. Serbinski· 1 shared Chunyan HouiD· 1 shared Curtis R. CarlsoniD· 1 shared Darcy A. KruegeriD· 1 shared David F. SmithiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersMolecular Biology

Andrew C. LiuORCID

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2 papers

Recent·Most cited

Divergent signaling profiles in mTOR gain-of-function Smith-Kingsmore syndrome (SKS) and TSC2 deficiency

Curtis R. Carlson, Yang Shen, Hongzhi He, Erwin Kristobal Gudenschwager Basso, Chunyan Hou, Junfeng R Ma, Joanna C. Chiu, Andrew C. Liu

The paper compares signaling profiles in SKS and TSC2 deficiency using proteomics, phosphoproteomics, and transcriptomics to show distinct regulatory states.

bioRxiv · May 13, 2026 · PreprintMolecular Biology

Detailed Clinical and Functional Studies of New MTOR Variants in Smith-Kingsmore Syndrome Reveal Deficits of Circadian and Sleep Homeostasis

Andrew C. Liu, Yang Shen, Destino Roman, Hongzhi He, Carolyn R. Serbinski, Lindsey Aschbacher‐Smith, Katherine A. King, Jorge Luis Granadillo, Isabel López, Darcy A. Krueger, Thomas J. Dye, David F. Smith, John B. Hogenesch, Carlos Enrique Prada

This study identifies new MTOR variants in Smith-Kingsmore Syndrome, reveals circadian and sleep deficits, and shows rapamycin treatment can improve symptoms.

medRxiv · Feb 15, 2022 · PreprintGenetic & Genomic Medicine