Joanna C. Chiu

This study shows that insecticide-resistant Drosophila suzukii exhibits increased global alternative splicing events, enriched in stress response and resistance processes, even without substantial differential gene expression.

The paper compares signaling profiles in SKS and TSC2 deficiency using proteomics, phosphoproteomics, and transcriptomics to show distinct regulatory states.

This study shows that alternative splicing of the timeless gene regulates seasonal adaptations in Drosophila by modulating PDF signaling through a winter gating mechanism.

This study shows that mealtime affects the daily rhythm of nuclear O-GlcNAc proteome in mice, which regulates hepatic gene expression through interactions with phosphorylation.

The paper investigates temperature-sensitive alternative splicing of the clk gene in Drosophila and its role in regulating circadian clock function through phosphorylation site deletion.

The paper shows that taste sensing in hungry flies triggers a warm temperature preference, which is distinct from nutrient-induced responses and regulated by clock genes and hunger signals.

This study identifies molecular mechanisms of pyrethroid and spinosad resistance in Drosophila suzukii through transcriptome analysis and validates findings using Drosophila melanogaster mutants.

This study shows CLOCK and TIMELESS regulate daily rhythmic BRM chromatin-remodeling activity at clock gene promoters in Drosophila.

This study shows that PDF signaling negatively modulates EYA levels to regulate seasonal physiology in Drosophila by integrating thermal and photoperiodic cues.

This paper identifies the role of PER phosphodegron residues in temperature compensation of the Drosophila circadian clock through genetic and biochemical experiments.

The paper investigates conformational changes in circadian clock negative arm proteins and their role in post-transcriptional regulation through dynamic interactomes.

The paper analyzes whole-genome sequences of Drosophila suzukii to identify population structure and migration patterns, finding strong East-West differentiation in the U.S. and repeated Asian migrations.

The paper identifies TIM phosphorylation sites in Drosophila and shows that CK2-dependent phosphorylation of TIM(S1404) regulates nuclear export and circadian rhythms, with implications for human FASPS.

This study identifies DOM splice variants DOM-A and DOM-B as regulators of circadian behavior and sLNv maintenance in Drosophila by modulating pacemaker gene expression and PDF accumulation.

This study analyzes genome-wide divergence in invasive Aedes aegypti populations in California, identifying three genetic clusters and evidence of hybridization among them.