Postsynaptic GluA3 subunits are required for the appropriate assembly of AMPA receptor GluA2 and GluA4 subunits on mammalian cochlear afferent synapses and for presynaptic ribbon modiolar-pillar morphological distinctions
Mark Allen Rutherford, Atri Bhattacharyya, Maolei Xiao, Hou-Ming Cai, Indra Pal, Maria Eulalia Rubio
This study shows that GluA3 is essential for the proper assembly of AMPAR subunits and presynaptic ribbon morphology in cochlear synapses, leading to hearing loss in mice.
eLife · Jan 17, 2023Peer-reviewedNeuroscience