Aberrant immune regulation and enrichment of stem-like CD8+ T cells in the pancreatic lymph node during type 1 diabetes development
Leeana D. Peters, Howard R. Seay, Justin Smith, Amanda L. Posgai, Reed L. Berkowitz, Clive H. Wasserfall, Mark A. Atkinson, Rhonda L. Bacher, Maigan Brusko, Todd M. Brusko
This study identifies aberrant immune regulation and stem-like CD8+ T cells in pancreatic lymph nodes during type 1 diabetes development using mass cytometry and single-cell RNA sequencing.
bioRxiv · May 23, 2025 · PreprintImmunology