Orphan nuclear receptors recruit TRIM28 to promote telomeric H3K9me3 for the alternative lengthening of telomeres pathway
Chia-Tsen Tsai, Venus Marie Gaela, Hsuan-Yu Hsia, Yu‐Chen Huang, Liuh‐Yow Chen
The paper shows orphan nuclear receptors recruit TRIM28 to increase H3K9me3 at telomeres, promoting the alternative lengthening of telomeres pathway in human cells.
bioRxiv · Jun 16, 2025 · PreprintMolecular Biology