Author

Venus Marie Gaela

Institute of Molecular Biology, Academia SinicaORCID 0000-0001-9039-627XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Hsuan-Yu Hsia· 2 shared Liuh‐Yow CheniD· 2 shared Chia-Tsen TsaiiD· 1 shared Thomas BoudieriD· 1 shared Yu‐Chen HuangiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersMolecular Biology

Hsuan-Yu Hsia

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 16, 2025

Orphan nuclear receptors recruit TRIM28 to promote telomeric H3K9me3 for the alternative lengthening of telomeres pathway

Chia-Tsen Tsai, Venus Marie Gaela, Hsuan-Yu Hsia…·Liuh‐Yow Chen

The paper shows orphan nuclear receptors recruit TRIM28 to increase H3K9me3 at telomeres, promoting the alternative lengthening of telomeres pathway in human cells.

1 citation

humanDNA methylation

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Molecular BiologybioRxivPreprintMar 30, 2022

Orphan nuclear receptors promote alternative lengthening of telomeres (ALT) through ALT-associated PML bodies

Venus Marie Gaela, Hsuan-Yu Hsia, Thomas Boudier, Liuh‐Yow Chen

This study shows that orphan nuclear receptors promote the ALT telomere maintenance mechanism by forming APBs and enabling telomeric DNA synthesis.

1 citation

humanexperimental assay

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