Pan-Prediction of MHC-II Restricted Epitopes Across Species via an Alphafold-based Quantification Scheme
Suqiu Wang, Lingming Kong, Hu Dongmei, Liangzhen Zheng, Caiyi Fei, Liubao Du, Ziche Tang, Malgorzata Anna Garstka, Onur Serçinoğlu, Lifeng Zhang, Sheng Wang, Shi Xu, Hanchun Yang, Nianzhi Zhang
This study introduces AF-pred, an Alphafold-based tool for cross-species prediction of MHC-II restricted epitopes, showing better performance for non-human MHC-II than sequence-based methods.
hLife · Jan 9, 2026Peer-reviewedImmunology