Resolving the Deep Sleep Dual Indeterminacy Problem: Context-Dependent Slow-Wave Activity Modeling Predicts Neurobehavioral Fatigue Where Clinical Sleep Modeling Fails
Shashaank Vattikuti, Hua Xie, Carson C. Chow, Thomas J. Balkin, John Hughes
The paper shows that slow-wave activity (SWA) predicts neurobehavioral fatigue differently during sleep and wakefulness, outperforming clinical sleep metrics in modeling recovery from sleep deprivation.
bioRxiv · Mar 28, 2026 · PreprintPhysiology