Author

John Hughes

Walter Reed Army Institute of ResearchORCID 0000-0002-2187-2911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:statistical model· 2 Assay:electronic health records· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Thomas J. BalkiniD· 2 shared Carson C. ChowiD· 1 shared Hua Xie· 1 shared Shashaank Vattikuti· 1 shared Tracy Jill DotyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersNeuroscience

Thomas J. BalkinORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 9, 2026

Slow Oscillatory Transcranial Direct Current Stimulation during a Restricted Sleep Opportunity Enhances Cognitive Performance during Subsequent Wakefulness

John Hughes, Tracy Jill Doty, Thomas J. Balkin

SO-tDCS during restricted sleep improves cognitive performance and memory retention during subsequent wakefulness compared to sham stimulation.

DOI 10.64898/2026.07.03.736438

humanelectronic health records

PhysiologybioRxivPreprintMar 28, 2026

Resolving the Deep Sleep Dual Indeterminacy Problem: Context-Dependent Slow-Wave Activity Modeling Predicts Neurobehavioral Fatigue Where Clinical Sleep Modeling Fails

Shashaank Vattikuti, Hua Xie, Carson C. Chow…·John Hughes

The paper shows that slow-wave activity (SWA) predicts neurobehavioral fatigue differently during sleep and wakefulness, outperforming clinical sleep metrics in modeling recovery from sleep deprivation.

2 citations

humanelectrophysiology