Profiling of Nascent Lariat Intermediates Reveals Key Genetic Determinants of the Timing of Human Co-transcriptional Splicing
Yi Zeng, Huilin Zeng, Benjamin Jung Fair, Aiswarya Krishnamohan, Yichen Hou, Johnathon M. Hall, Alexander J. Ruthenburg, Yang Li, Jonathan P. Staley
The paper introduces CoLa-seq to profile splicing timing and identifies genetic factors influencing co-transcriptional splicing in human cells.
bioRxiv · Oct 18, 2021 · PreprintMolecular Biology