NeuroscienceBiomoleculesPeer-reviewed
Enhanced anti-nociception by novel dual antagonists for 5HT2aR and mGluR5 in preclinical models of pain
Daekyu Choi, Hyun Jin Heo, Hae‐Young Shin…·Hanmi Lee
This study shows that dual antagonism of 5-HT2AR and mGluR5 enhances anti-nociception in pain models, with efficacy comparable to gabapentin and morphine, but without tolerance or abuse potential.
3 citations