Hyunjin Shim

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

This study evaluates favipiravir's effectiveness against influenza A virus by analyzing mutation rates and population dynamics under varying drug concentrations.

On the importance of skewed offspring distributions and background selection in viral population genetics

The paper discusses the impact of skewed offspring distributions and background selection on viral population genetics and highlights challenges in genetic inference.

Detecting and quantifying changing selection intensities from time-sampled polymorphism data

This paper introduces a method to detect and quantify non-random changes in selection intensities using ABC-based approaches, applied to historical and influenza virus data.

WFABC: a Wright-Fisher ABC-based approach for inferring effective population sizes and selection coefficients from time-sampled data

The paper compares ABC-based methods for inferring population genetic parameters from time-sampled data and demonstrates the effectiveness of a new approach for estimating effective population size and selection coefficients.