Matthieu Foll

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy

This study evaluates favipiravir's effectiveness against influenza A virus by analyzing mutation rates and population dynamics under varying drug concentrations.

Detecting and quantifying changing selection intensities from time-sampled polymorphism data

This paper introduces a method to detect and quantify non-random changes in selection intensities using ABC-based approaches, applied to historical and influenza virus data.

Worldwide population structure, long term demography, and local adaptation of Helicobacter pylori

This study analyzes the global population structure and demography of Helicobacter pylori, identifying ancient human association and candidate genes under positive selection.

Thinking too positive? Revisiting current methods of population-genetic selection inference

This paper discusses improvements in population-genetic selection inference by advocating for simulation tools, multi-time point genomic data, and experimental evolution results.

WFABC: a Wright-Fisher ABC-based approach for inferring effective population sizes and selection coefficients from time-sampled data

The paper compares ABC-based methods for inferring population genetic parameters from time-sampled data and demonstrates the effectiveness of a new approach for estimating effective population size and selection coefficients.