Lipids Regulate Export of Lysosomal Enzymes from the Endoplasmic Reticulum
Baolong Xia, Myeonghoon Han, I Park, Norbert Perrimon
The paper shows that de novo lipogenesis regulates lysosomal enzyme export from the ER by promoting Arf1 myristoylation and retrograde vesicle trafficking.
Proceedings of the National Academy of Sciences · Sep 17, 2026Peer-reviewedCell Biology