Longitudinal tracking of Plasmodium falciparum clones in complex infections by amplicon deep sequencing
A. Lerch, C. Koepfli, N. E. Hofmann, J. H. Kattenberg, A. Rosanas-Urgell, I. Betuela, I. Mueller, I. Felger
This study compares Amp-Seq and length-polymorphism genotyping for tracking Plasmodium falciparum clones in longitudinal infections, finding Amp-Seq more sensitive for detecting minority clones.
bioRxiv · Apr 30, 2018Microbiology