A weak Foxp3 hypomorph enhances spontaneous and therapeutic immune surveillance of cancer in mice
J. Almeida-Santos, M.-L. Bergman, I. A. Cabral, V. Correia, I. Caramalho, J. Demengeot
This study shows that a weak Foxp3 hypomorph allele enhances anti-tumor immunity in mice, reducing tumor growth and improving response to immunotherapy.
bioRxiv · Mar 7, 2019Cancer Biology