Precursor miRNAs are trafficked along axons associated with vesicles and locally processed to regulate growth cone steering
E. Corradi, A. Gavoci, S. Strohbuecker, M. Roccuzzo, I. Dalla Costa, A. Iyer, S. Bridi, G. Santoz Rodriguez, C. Abreu-Goodger, M.-L. Baudet
The paper shows that precursor miRNAs are transported along axons, processed into mature miRNAs, and regulate growth cone steering by inhibiting TUBB3 translation.
bioRxiv · Nov 14, 2018Cell Biology