Author

I. Dzhygyr

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Garcia-Pino· 1 shared G. Akanuma· 1 shared G. C. Atkinson· 1 shared H. Takada· 1 shared M. Roghanian· 1 shared R. Murayama· 1 shared V. Hauryliuk· 1 shared V. Murina· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

A. Garcia-Pino

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1 paper

Recent·Most cited

The C-terminal RRM/ACT domain is crucial for fine-tuning the activation of 'long' RelA-SpoT Homolog enzymes by ribosomal complexes

H. Takada, M. Roghanian, V. Murina, I. Dzhygyr, R. Murayama, G. Akanuma, G. C. Atkinson, A. Garcia-Pino, V. Hauryliuk

This study shows that the RRM domain in long RSH enzymes is essential for proper ribosome-mediated activation, preventing excessive (p)ppGpp production and cytotoxicity.

bioRxiv · Jan 23, 2020Biochemistry