Loss of COX4i1 leads to combined respiratory chain deficiency and impaired mitochondrial proteosynthesis
K. Cunatova, D. Pajuelo Reguera, M. Vrbacky, E. Fernandez-Vizarra, S. Ding, I. Fearnley, M. Zeviani, J. Houstek, T. Mracek, P. Pecina
This study shows that loss of COX4i1 causes combined respiratory chain deficiency and impaired mitochondrial proteosynthesis by disrupting cI and cIV biogenesis.
bioRxiv · Jan 31, 2020 · PreprintBiochemistry