Author

P. Pecina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Pecinova· 3 shared J. Houstek· 3 shared M. Vrbacky· 3 shared T. Mracek· 3 shared K. Cunatova· 2 shared K. Tauchmannova· 2 shared V. Kaplanova· 2 shared A. Benda· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

A. Pecinova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bioenergetics of human spermatozoa in patients with testicular germ cell tumour

O. Simonik, B. Bryndova, V. P. Sur, L. Ded, Z. Cockova, A. Benda, M. Qasemi, P. Pecina, A. Pecinova, D. Spevakova, T. Hradec, P. Skrobanek, Z. Ezrova, Z. Kratka, R. Kren, , K. Komrskova

This study examines the bioenergetic patterns of cryopreserved sperm from testicular germ cell tumor patients compared to normozoospermic samples using XF Analyzer and 2P-FLIM, revealing cryopreservation-induced metabolic impairments.

bioRxiv · May 24, 2024Cell Biology

Physiological variability in mitochondrial rRNA predisposes to metabolic syndrome

P. Pecina, K. Cunatova, V. Kaplanova, G. Puertas-Frias, J. Silhavy, K. Tauchmannova, M. Vrbacky, T. Cajka, O. Gahura, M. Pravenec, J. Houstek, T. Mracek, A. Pecinova

The paper investigates how mitochondrial rRNA sequence variation contributes to insulin resistance and metabolic syndrome in rats fed a high-fat diet.

bioRxiv · Nov 8, 2023Physiology

MLQ is responsible for stabilisation of subunit a in the holoenzyme of mammalian ATP synthase

K. Tauchmannova, H. D. Ho, H. Nuskova, A. Pecinova, L. Alan, M. Rodinova, E. Konarikova, M. Vrbacky, G. Puertas, V. Kaplanova, J. Houstek, P. Pecina, T. Mracek

This paper investigates the role of MLQ in ATP synthase biogenesis, finding that MLQ stabilizes the holoenzyme and its absence leads to labile, functional but ATP-synthesizing-defective complexes.

bioRxiv · Feb 3, 2020 · PreprintBiochemistry

Loss of COX4i1 leads to combined respiratory chain deficiency and impaired mitochondrial proteosynthesis

K. Cunatova, D. Pajuelo Reguera, M. Vrbacky, E. Fernandez-Vizarra, S. Ding, I. Fearnley, M. Zeviani, J. Houstek, T. Mracek, P. Pecina

This study shows that loss of COX4i1 causes combined respiratory chain deficiency and impaired mitochondrial proteosynthesis by disrupting cI and cIV biogenesis.

bioRxiv · Jan 31, 2020 · PreprintBiochemistry